An Assessment of the Readiness for Introduction of the HPV Vaccine in Uganda

Katahoire RA(1), Jitta J(2), Kivumbi G(3), Murokora D(4), Arube Wani J(5), Siu G(6), Arinaitwe L(7), Mugisha E(8), Bingham A(9), Tsu V(10), LaMontagne D.S(11),


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Corresponding Author

Abstract


Formative research assessing human papillomavirus (HPV) vaccine readiness in Uganda was conducted in 2007. The objective was to generate evidence for government decision-making and operational planning for HPV vaccine introduction. Qualitative research methods with children, parents, teachers, community leaders, health workers, technical experts and political leaders were used to capture understanding of socio-cultural, health system and policy environments. We found low levels of knowledge about cervical cancer and HPV. Vaccination and its benefits were well-understood; respondents were positive about HPV vaccination. Health systems were deemed adequate for HPV vaccine delivery. Schools were identified as a vaccination venue, given high attendance by girls aged 10-12 years. Communication and advocacy strategies to foster acceptance should provide information on cervical cancer, HPV vaccine safety, and side effects. Policymakers requested further detail on costs. Introduction of HPV vaccine could be integrated into existing reproductive health and immunization policies (Afr J Reprod Health 2008; 12[3]:159-172).

 

RĖSUMĖ         

Une évaluation de l’empressement pour l’introduction du vaccin PVH en Ouganda  Une étude formatrice pour l’évaluation de l’empressement du vaccin papillomavirus humain (PVH) en Ouganda a été menée en 2007. L’objectif a été de généré la preuve pour la prise de décision par le gouvernement et la planification opérationnelle pour l’introduction du vaccin PVH. Les méthodes de recherche qualificative avec les enfants, les parents, les enseignants, les leaders des communautés, les dispensateurs, les experts techniques et les leaders politiciens se sont servis pour attirer la compréhension socioculturelle, du système sanitaire et la politique des environnements. Nous avons découvert des niveaux bas du cancer du col et la vaccination de PVH. La vaccination et ses bénéfices sont considérées adéquats pour la livraison du vaccin PVH. Les écoles ont été identifiées comme centre de vaccination étant donnée la fréquentation élevée des filles âgées de10-12 ans. La communication et les stratégies de plaidoyer en cause d’encourager l’acceptation doit fournir des informations sur le cancer du col, la sûreté du vaccin PVH et ses conséquences. Les décideurs de politique ont demandé pour plus de détails sur les prix. L’introduction du vaccin PVH pourrait être intégrée dans les politiques de la santé de reproduction et d’immunisation (Afr J Reprod Health 2008; 12[3]:159-172).

 

 

KEY WORDS:  Human papillomavirus, vaccine, formative research, cervical cancer, Uganda


References


Parkin DM, International Agency for

Research on Cancer (IARC). Cancer in Africa: epidemiology and prevention. Lyon, France: IARC Press; 2003.

Wabinga HR, Parkin DM, Wabwire-Mangen F, Nambooze S. Trends in cancer incidence in Kyadondo County, Uganda, 1960-1997. Br J Cancer 2000 May;82(9):1585-92.

Wabinga H, Ramanakumar AV, Banura C, Luwaga A, Nambooze S, Parkin DM.

Survival of cervix cancer patients in Kampala, Uganda: 1995-1997. Br J Cancer 2003 July 7;89(1):65-9.

Gondos A, Brenner H, Wabinga H, Parkin DM. Cancer survival in Kampala, Uganda. Br J Cancer 2005 May 9;92(9):1808-12.

McArdle O, Kigula-Mugambe JB.

Unexpectedly high rates of grade 3 and 4 acute toxicity in the treatment of cervical cancer in sub-Saharan Africa. Gynecol Oncol 2007 March;104(3):779-80.

Wittet S. Cervical cancer vaccine project. [Fact sheet]. Seattle: PATH; 2006.

Green LW, Kreuter MW, Green LW. Health program planning: an educational and ecological approach. New York: McGraw-

Hill; 2005.

Sallis J, Owen N. Ecological models of health behavior. In: Glanz K, Rimer BK, Lewis FM, editors. Health behavior and health education: theory, research, and practice. 3rd ed. San Francisco: Jossey-Bass; 2002. p. 462-84.

Bingham A, Janmohameda A, Bartolini R, Creed-Kanashiro HM, Katahoire AR, Khan I,

Lyazi I, Menezes L, Murokora D, Quy NN,

Tsu V. An approach to formative research in HPV vaccine introduction planning in lowresource settings. The Open Vaccine Journal, 2008; 1:45-60.

Miles MB, Huberman AM. Qualitative data analysis: an expanded sourcebook. Thousand Oaks: Sage Publications; 1994.

MacQueen KM, McLellan-Lemal E,

Barthalow K, Milstein B. Team-based codebook development : structure, process, and agreement. In: Guest G, MacQueen KM, editors. Handbook for team-based qualitative research. Lanham: Altamira; 2008. p. 11936.

Jitta J. Review of the Child Days Plus strategy. Kampala: Child Health and Development Centre, Makerere University; 2007. Available at: www.chdc-mukcom/ Summaries/Microsoft%20Word%20-%20CD PS%20summary.pdf.

World Health Organization, United Nations Population Fund. Preparing for the introduction of HPV vaccines: policy and programme guidance for countries. Geneva: World Health Organization; 2006.

Piotrow PT, Kincaid DL, Rimon JG, Rinehart W, Samson K. Health communication: lessons from family planning and reproductive health. Westport, Connecticut: Praeger; 1997.

Sherris J, Friedman A, Wittet S, Davies P, Steben M, Saraiya M. Chapter 25: Education, training, and communication for HPV vaccines. Vaccine 2006 August 21;24(Suppl. 3):S210-S218.

Waisbord S, Larson HJ. Why invest in communication for immunization? Evidence and lessons learned. Baltimore: Johns Hopkins Bloomberg School of Public Health, Center for Communication Programs, Health Communication Partnership; 2005.

Wittet S. Hepatitis B vaccine introduction: lessons learned advocacy, communication and training. Seattle: PATH; 2001. Available at: www.path.org/vaccineresources/files/CVP _Occ_Paper4.pdf.

Younger E, Wittet S, Hooks C, Lasher H. Immunization and Child Health Materials Development Guide. Seattle: PATH; 2001.

Clemens JD, Jodar L. Translational research to assist policy decisions about introducing new vaccines in developing countries. J Health Popul Nutr 2004; 22(3):223-31.

DeRoeck D. The importance of engaging policy-makers at the outset to guide research on and introduction of vaccines: the use of policy-maker surveys. J Health Popul Nutr 2004 September;22(3):322-30.


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