Prevalence of Low Sperm Count and Abnormal Semen Parameters in Male Partners of Women Consulting at Infertility Clinic in Abakaliki, Nigeria

Ugwuja E.I, Ugwu N.C, Ejikeme B.N

Abstract

In order to provide an insight to the prevalence of low sperm count and abnormal semen parameters in suspected subfertile/infertile men in our environment, semen samples collected from one hundred and seventy (170) men aged 21-50 years, whose wives were seen at a private fertility clinic in Abakaliki, Nigeria with diagnosis of primary and secondary infertility (78 and 92 respectively) were analysed in accordance with World Health Organization guidelines.

Significantly high proportion (70%) of the study population had low sperm count (p < 0.05) with significantly high defective parameters (64%). Asthenozoospermia and teratozoospermia were the major abnormal parameters recorded. Higher prevalence of oligospermia was found in the civil servants and age-group 31-40 years (74% and 75% respectively). Using 105 cfu/ml as a significant level of bacteria growth, the prevalence of bacteria growth was found to be 56% of which 18% were from normospermic semen d 38% from oligospermic semen. (Afr Reprod Health 2008; 12[1]:67-73).

RÉSUMÉ

Prévalence du paludisme au moment de se présenter pour la première fois chez les clientes anténatales dans un établissement de santé secondaire à Ibadan, Nigeria. La prévalence de la parasitémie du paludisme au moment de se présenter pour la première fois a été étudiée chez 1,848 femmes enceintes dans un hôpital secondaire à Ibadan, Nigeria.  Les principales issues variables étaient la parasitémie persistante et la fièvre 8,4% (155) avaient la parasitémie du paludisme persistant.  La majorité (89%) des participantes qui avaient la parasitémie étaient asymptomatiques. Les participantes fébriles se sont inscrites à un âge gestationnel plus tôt (22,7 par opposition à 24, 2 semaines) plus que les patientes afébriles (p = 0,0052).  L’anémie était plus prévalente parmi les patientes qui avaient la parasitémie persistante (58,1%) que chez celle qui n’en avaient pas (58,1% par opposition à 22,6% p < 0,0001).  La parasitémie du paludisme était plus élevée chez les femmes nullipares que chez les autres groupes de parité (p < 0, 0001).  La prévalence de la parasitemie du paludisme dans cette étude est beaucoup plus basse que dans les rapports précédents.  Le paludisme symptomatique a été lié à l’inscription faite tôt pout l’hygiène de la grossesse et la parasitémie du paludisme était un déterminent important de l’anémie. (Rev Afr Santé Reprod 2008; 12[1]:67-73).

 

KEY WORDS:  Abnormal semen parameters, male partners, genital infection, infertility.

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References

Larsen U. Primary and secondary infertility in subSaharan Africa. Int. J. Epidemiol 2000; 29 (2): 285-91.

Fayig E, Ibrahim B, Saleem AB. Clinico-hormonal correlation of oligospermic patients in the below sea level environment (Jordan Valley).

Neuroendocrinol Let. 2005; 26 (1): 13-18.

Adetoro OO, Ebomoyi EW. The prevalence of infertility in a rural Nigerian community. Afr. J. Med. Sci 1991; 20 (1): 23-7.

Ikechebelu JI, Adinma JI, Orie EF, Ikegwonu SO. High prevalence of male infertility in Southeastern Nigeria. J. Obstet. Gynaecol. 2003; 23 (6): 657-9.

Weber RF, Dohle GR, Romijin JC. Clinical laboratory evaluation of male subfertility. Adv. Clin. Chem. 2005; 40: 317-64.

Dua A, Vaidya SR. Sperm motility and morphology as changing parameters linked to sperm count variations. J. Postdrad. Med. 1996; 42: 93-96.

Gyllenborg J, Skakebeak NE, Nielsen NC, Keiding N, Giwercman A. Secular and seasonal changes in semen quality among young Danish men: a statistical analysis of semen samples from 1927 donor candidates during 1977-1995. Int. J. Androl. 1999; 22 (1): 28-36.

Dohle GR. Inflammatory-associated obstructions of the male reproductive tract. Andrologia 2003; 35 (5): 321-4.

WHO Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. Cambridge University Press 3rd edition, 1992.

Cheesbrough M. District laboratory practice inTropical countries part 2. Cambridge University Press, 2000.

Pontonnier F, Bujan L. [How to recognize andclassify male infertility]. Rev. Prat. 1993; 43 (8): 941-7.

Kurzawa R, Kozanecka A, Glabowski W,

Malonowska D, Rozewicki S. The analysis of sper parameters in view of its concentration and motility in relation to men’s age and occupation. Ginekol. Pol. 1998; 69 (6): 460-5.

Chia SE, Lim ST, Tay SK. Factors associated withmale infertility: Sperm characteristics, strict criteria sperm morphology analysis and hypoosmotic swelling test. B.J.O.G. 2000; 107 (1): 55-61.

Mogra NN, Dhruva AA, Kothari LK. Non-specificseminal tract infection and male infertility: a bacteriological study. J. Posgrad Med. 1981; 27 (2): 99-104.

Tomlinson MJ, Barratt CL and Cooke ID. Prospectivestudy of leucocytes and leucocyte subpopulation in semen suggests they are not a cause of male infertility. Fertil. Steril. 1994; 62 (1): 206-7.

Aziz N, Agarwal A, Lewis-Jones I, Sharma RKand Thomas AJ (Jr). Novel association between specific sperm morphological defects and leucocytospermia. Fertil. Steril. 2004; 82 (3): 621-7.

Lemkecher T, Dartigues S, Veysse J, Kulski O,Barraud-Lange V, Gattegno L and Wolf JP. Leucocytospermia, oxidative stress and male infertility: facts and hypotheses. Gynaecol. Obstet. Fertile 2005; 33 (1-2): 2-10.

Krause W, Habermann B. no change with age insemen volume, sperm count and sperm motility in individual men consulting an infertility clinic. Urol. Int. 2000; 64 (3): 139-42.

Jung A, Schuppe HC, Schill WB. Comparison ofsemen quality in older and younger men attending an andrology clinic. Andrologia 2000; 34 (2): 116-22.

Rolf C, Kenkel S, Nieschlag E. Agr-related diseasepattern in infertile men: Increasing incidence of infection in older patients. Andrologia 2002; 34 (4): 209-17.

Chen Z, Toth T, Godfrey-Bailey L, Mercedat N,Schiff I and Hauser R. Seasonal variation and agrrelated changes in human semen parameters. J. Androl. 2003; 24 (2): 226-31.

Andrade-Rocha FT. semen parameters in men withsuspected infertility: Sperm concentrations, strict criteria sperm morphology, analysis and hypoosmotic swelling test. J. Reprod. Med 2001; 46 (6): 577-82.

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