Deficiency of alpha-Tocopherol in Seminal Fluid as a Probable Factor in Low Fertility in Côte d’Ivoire
), Gildas K. Gbassi(2),
(1)
(2)
Corresponding Author
Abstract
To evaluate the level of alpha-Tocopherol in seminal fluid of patients with low fertility, forty subjects with low fertility (17 with asthenospermia and 32 with oligoasthenospermia) and 21 subjects with normal sperm parameters were recruited into this study for assessing their alpha-Tocopherol seminal fluid level. The mean level of alpha-Tocopherol in subjects with normal sperm profile was 0.62 µmol/l compared to those with pathological profile such as asthenospermia (0.29 µmol/l) and oligoasthenospermia (0.28 µmol/l). The determination of alpha-Tocopherol in human seminal fluid provides useful information concerning the exploration of low fertility in Cote d’Ivoire (Afr J Reprod Health 2009; 13[3]:123-125).
RĖSUMĖ
Carence en alpha-tocophérol du liquide séminal comme facteur potentiel de l’hypo-fertilité en Côte-d’Ivoire. Nous avons effectué cette étude afin d’évaluer la carence en alpha-tocophérol du liquide séminal des patients souffrant de l’hypo-fertilité masculine. Nous avons retenu dans l’étude 49 couples dont les maris souffraient de l’hypo-fertilité (17 asthénospermiques et 32 oligoasthénospermiques) et 21 couples normaux pour l’évaluation de leur carence séminale en alpha-tocophérol. La carence moyenne en alpha-tocophérol des sujets normaux était de 0,62 µmol/1 comparé aux profiles pathologiques (0,29 µmol/1) pour les asthénospermiques et 0,28 µmol/1 pour les oligoasthénospermiques. L’évaluation de la carence en alpha-tocophérol du liquide séminal humain a fourni des informations utiles concernant l’exploration de l’hypo-fertilité conjugale en Côte d’Ivoire (Afr J Reprod Health 2009; 13[3]:123-125).
KEYWORDS: alpha-Tocopherol; Seminal fluid; Hypofertility; Cote d’Ivoire.
References
Kessopoulou E, Powers HJ, Sharma KK, Pearson MJ, Russel JM, Cook ID et al. A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated male infertility. Fertil Steril 1995; 64(4): 825-31.
Laudat A, Lecourbe K and Palluel AM. Peroxydation lipidique, profil morphologique de stress testiculaire et maturité nucléaire des spermatozoides. Ann Biol Clin 1999; 57: 51-6.
Lewis SEM, Sterling ES, Young IS and Thompson W. Comparison of individual antioxidant of sperm and seminal plasma in fertile and infertile men. Fertil Steril 1997; 67(1):142-7.
Omu AE, Fatinikum T, Mannazhath N and
Abraham S. Significance of simultaneous determination of serum and seminal plasma alpha-tocopherol and retinol in infertile men by high performance liquid chromatography. Andrologia 1999; 31(6):347-54.
Suleiman SA, Elamin AM, Zaki ZMS, El Malik EMA and Nasr MA. Lipid peroxidation and human sperm motility : Protective role of vitamin E. J Androl 1996; 17(5): 530-7.
Therond P, Auger J, Legrand A and Jouannet P. α-tocopherol in human spermatozoa and seminal plasma: relationships with motility, antioxidant enzymes and leukocytes. Mol Hum Reprod 1996; 2(10): 739-44.
World Health Organization (WHO).
Laboratory Manual for the examination of human semen and sperm-cervical mucus interaction. 4th ed. Cambridge University Press; 1999: p.138.
African Journal of Reproductive Health Vol 13 No 3 September 2009
African Journal of Reproductive Health
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