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Effectiveness of transurethral resection combined with sapylin for bladder perfusion in glandular cystitis: A randomized controlled trial

Yi Guan(1), Changbin Tan(2), Fei Xiao(3), Haoyong Li(4), Haitao Liu(5), Wei Hu(6), Huajie Song(7), Hengcheng Zhu(8),


(1) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(2) Department of Urology, E Zhou Center Hospital, E Zhou, Hubei 436099, China
(3) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(4) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(5) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(6) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(7) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(8) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
Corresponding Author

Abstract


This study explored the impact of transurethral resection plus sapylin for bladder perfusion in treating glandular cystitis. One hundred and twenty-eight cases of glandular cystitis who accepted therapy in Renmin Hospital of Wuhan University, Wuhan, China from September 2018 to September 2022 were chosen and randomly separated into a control group (CG, n=64) and a research group (RG, n=64). The CG received transurethral resection. In contrast, the RG received sapylin infusion chemotherapy in addition to transurethral resection. The clinical efficacy, urination function, levels of inflammatory factors, quality of life along with adverse reactions in the two groups was compared. Relative to the CG, the RG showed higher total treatment effectiveness rate, better improvements of urination function and inflammation, higher quality of life scores, and lower occurrence of adverse reactions. We conclude that transurethral resection combined with sapylin for bladder perfusion has higher effectiveness in treatment of glandular cystitis when compared to transurethral resection alone.

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