Role of neutrophils in the immune microenvironment of endometriosis

Jinghan Zhang(1), Shanshan Mei(2), Xinyan Wang(3),


(1) The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China
(2) Department of Gynaecology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310003, China
(3) Department of Gynaecology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310003, China
Corresponding Author

Abstract


Endometriosis (EMs) is a common systemic estrogen-dependent chronic inflammatory disease in gynaecology. Available evidence indicates that immune factors exert extremely important functions in the pathogenesis of EMs. As a key cell group in the immune environment, neutrophils have been found to be implicated in EMs progression in various studies. In this paper, the function and mechanism of neutrophils in the immune microenvironment of EMs are summarized, providing new research ideas for the etiology and pathogenesis of EMs.

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