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Clinical effects of laparoscopic versus open radical prostatectomy in the treatment of early prostate cancer

Yi Guan(1), Changbin Tan(2), Hengcheng Zhu(3), Haoyong Li(4), Haitao Liu(5), Wei Hu(6), Huajie Song(7), Fei Xiao(8),


(1) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(2) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(3) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(4) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(5) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(6) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(7) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
(8) Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430200, China
Corresponding Author

Abstract


The objective of this study was to investigate the clinical effects of laparoscopy vs open radical prostatectomy in treating early prostate cancer. Eighty-six early prostate cancer patients accepted therapy in Renmin Hospital of Wuhan University from January 2020 to June 2022 were chosen to be the study participants. They were randomly divided into a control group (CG) and a study group (SG). The CG received open radical prostatectomy. By contrast, the SG underwent laparoscopic radical prostatectomy. Relative to the CG, the SG presented longer surgery time, shorter hospital stay, drainage tube indwelling time, urinary catheter indwelling time and gastrointestinal function recovery time, less intraoperative blood loss, lower occurrence of postoperative intestinal obstruction, and lower occurrence of urinary incontinence after one week, one month and there months after surgery. The SG also had lower the postvoid residual urine, reduced international prostate symptom score, and elevated maximum urinary flow rate at six months after surgery. We conclude that laparoscopic surgery for early prostate cancer is associated with clearer vision, less trauma, less intraoperative bleeding, faster postoperative recovery, and fewer complications as compared to open radical prostatectomy, and has more valuable for clinical outcomes.

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