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Short-term efficacy of laparoscopic type C radical hysterectomy by deep uterine vein approach for treatment of cervical cancer

Juanpeng Yuhi(1), Ting Wang(2), Shengsheng Yu(3), Yingchun Gao(4),


(1) Department of Gynecology, The Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu 223300, China
(2) Department of Gynecology, The Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu 223300, China
(3) Department of Gynecology, The Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu 223300, China
(4) Department of Gynecology, The Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu 223300, China
Corresponding Author

Abstract


This was an original research. The objective of the study was to investigate the efficacy of laparoscopic type C radical hysterectomy by deep uterine vein approach in treating cervical cancer. Two hundred cases of cervical cancer were allocated into control group and intervention group. The control group underwent pelvic lymph node dissection + para-aortic lymph node resection followed by extensive hysterectomy. The intervention group underwent laparoscopic type C radical hysterectomy by deep uterine vein approach + pelvic lymph node dissection ± para-aortic lymph node resection. In comparison with the control group, the intervention group had significantly lower amount of blood loss, longer time of indwelling catheter, shorter time of abdominal drainage tube removal and anal exhaust, lower incidence of postoperative complications, higher rate of pathological stage upgrading, and higher quality of life score, and had lower recurrence rate. We conclude that laparoscopic C-type radical hysterectomy by deep uterine vein approach is effective, safe and reliable, and can promote patients quality of life, which is valuable for clinical use.

References


Mitra T and Elangovan S. Cervical cancer development,

chemoresistance, and therapy: a snapshot of

involvement of microRNA. Mol Cell Biochem.

; 476(12):4363-4385.

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram

I, Jemal A and Bray F. Global Cancer Statistics 2020:

GLOBOCAN Estimates of Incidence and Mortality

Worldwide for 36 Cancers in 185 Countries. CA

Cancer J Clin. 2021; 71(3):209-249.

Liang MR, Han DX, Jiang W, Liu H, Li L, Zhong ML, Luo

L and Zeng SY. [Laparoscopic type C1 hysterectomy

based on the anatomic landmark of the uterus deep

vein and its branches for cervical cancer]. Zhonghua

Zhong Liu Za Zhi. 2018; 40(4):288-294.

Horie A, Abiko K, Baba T, Sunada M, Kitamura S, Yamanoi

K, Horikawa N, Yamaguchi K, Hamanishi J, Kondoh

E and Mandai M. A Novel Direct Approach to the

Deep Uterine Vein in Laparoscopic Radical

Hysterectomy. J Minim Invasive Gynecol. 2021;

(8):1444-1445.

Bhatla N, Aoki D, Sharma DN and Sankaranarayanan R.

Cancer of the cervix uteri. Int J Gynaecol Obstet.

; 143 Suppl 2:22-36.

Wongkongdech R, Pansila N, Nonetoom P, Turnbull N and

Wongkongdech A. Symptom Management and

Quality of Life of Palliative Cancer Patients After

Being Administered with Thai Medicinal Cannabis.

Stud Health Technol Inform. 2022; 295:450-453.

Centini G, Afors K, Murtada R, Castellano J, Lazzeri L,

Fernandes R and Wattiez A. Step-by-step Type C

Laparoscopic Radical Hysterectomy With Nervesparing Approach. J Minim Invasive Gynecol. 2015;

(4):545.

Ramirez PT, Frumovitz M, Pareja R, Lopez A, Vieira M,

Ribeiro R, Buda A, Yan X, Shuzhong Y, Chetty N,

Isla D, Tamura M, Zhu T, Robledo KP, Gebski V,

Asher R, Behan V, Nicklin JL, Coleman RL and

Obermair A. Minimally Invasive versus Abdominal

Radical Hysterectomy for Cervical Cancer. N Engl J

Med. 2018; 379(20):1895-1904.

Melamed A, Margul DJ, Chen L, Keating NL, Del Carmen

MG, Yang J, Seagle BL, Alexander A, Barber EL,

Rice LW, Wright JD, Kocherginsky M, Shahabi S

and Rauh-Hain JA. Survival after Minimally

Invasive Radical Hysterectomy for Early-Stage

Cervical Cancer. N Engl J Med. 2018; 379(20):1905-

Park JY and Nam JH. How should gynecologic oncologists

react to the unexpected results of LACC trial? J

Gynecol Oncol. 2018; 29(4):e74.

Poddar P and Maheshwari A. Surgery for cervical cancer:

consensus & controversies. Indian J Med Res. 2021;

(2):284-292.

Yang FC, Huang W, Yang W, Liu J, Ai G, Luo N, Guo J,

Chua PT and Cheng Z. Cervical Cancer Surgery:

Current State of Affairs. Gynecol Minim Invasive

Ther. 2021; 10(2):75-83.

Campos LS, Limberger LF, Stein AT and Caldas JM.

Survival after Laparoscopic versus Abdominal

Radical Hysterectomy in Early Cervical Cancer: A

Randomized Controlled Trial. Asian Pac J Cancer

Prev. 2021; 22(1):93-97.

Zhao D, Li B, Zheng S, Ou Z, Zhang Y, Wang Y, Liu S,

Zhang G and Yuan G. Separate lateral parametrial

lymph node dissection improves detection rate of

parametrial lymph node metastasis in early-stage

cervical cancer: 10-year clinical evaluation in a

single center in China. Chin J Cancer Res. 2020;

(6):804-814.

Buskwofie A, David-West G and Clare CA. A Review of

Cervical Cancer: Incidence and Disparities. J Natl

Med Assoc. 2020; 112(2):229-232.

Koh WJ, Abu-Rustum NR, Bean S, Bradley K, Campos SM,

Cho KR, Chon HS, Chu C, Clark R, Cohn D,

Crispens MA, Damast S, Dorigo O, Eifel PJ, Fisher

CM, Frederick P, Gaffney DK, Han E, Huh WK,

Lurain JR, Mariani A, Mutch D, Nagel C,

Nekhlyudov L, Fader AN, Remmenga SW, Reynolds

RK, Tillmanns T, Ueda S, Wyse E, Yashar CM,

McMillian NR and Scavone JL. Cervical Cancer,

Version 3.2019, NCCN Clinical Practice Guidelines

in Oncology. J Natl Compr Canc Netw. 2019;

(1):64-84.

Zhang J, Song C and Liu B. Efficacy of cisplatin plus

paclitaxel as chemotherapy in patients with cervical

cancer after laparoscopic nerve-sparing extensive

hysterectomy and its effect on immune function. Pak

J Pharm Sci. 2022; 35(1(Special)):355-359.

Lee SH, Bae JW, Han M, Cho YJ, Park JW, Oh SR, Kim

SJ, Choe SY, Yun JH and Lee Y. Efficacy of nervesparing radical hysterectomy vs. conventional radical

hysterectomy in early-stage cervical cancer: A

systematic review and meta-analysis. Mol Clin

Oncol. 2020; 12(2):160-168.

Zhao D, Li B, Wang Y, Liu S, Zhang Y and Yuan G.

Clinical Outcomes in Early Cervical Cancer Patients

Treated with Nerve Plane-sparing Laparoscopic

Radical Hysterectomy. J Minim Invasive Gynecol.

; 27(3):687-696.

Gil-Ibáñez B, Díaz-Feijoo B, Pérez-Benavente A, Puig-Puig

O, Franco-Camps S, Centeno C, Xercavins J and GilMoreno A. Nerve sparing technique in roboticassisted radical hysterectomy: results. Int J Med

Robot. 2013; 9(3):339-44.


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