The impact of high temperatures on spontaneous abortion: A systematic review and meta-analysis
), Shyamkumar Sriram(2),
(1) Department of Family and Community Medicine and Medical Education, College of Medicine, Taibah University, Madinah 42353, Saudi Arabia; Health and Life Research Center, Taibah University, Madinah 42353, Saudi Arabia
(2) Department of Rehabilitation and Health Services, College of Health and Public Service, University of North Texas, Denton 76203, TX, USA
Corresponding Author
Abstract
References
Larsen EC, Christiansen OB, Kolte AM, Macklon N. New
insights into mechanisms behind miscarriage. BMC
Med 2013; 11(1): 154.
Lu Y, Zhang Y, Guan Q, Xu L, Zhao S, Duan J, Wang Y, Xia
Y, Xu Q. Exposure to multiple trace elements and
miscarriage during early pregnancy: A mixtures
approach. Environment International 2022; 162:
Wood S. Medical management of missed abortion: a
randomized clinical trial. Obstetrics & Gynecology
; 99(4): 563–6.
Zhao S, Xu J, Li W, Lu Y, Huang L, Xu H, Shi M, Wang Y,
Zhu Q, Xu Q. High-temperature exposure and risk of
spontaneous abortion during early pregnancy: a case
control study in Nanjing, China. Environ Sci Pollut
Res 2022; 30(11): 29807–13.
Weng S, Chang J, Yeh M, Wang S, Lee C, Chen Y. Do
stillbirth, miscarriage, and termination of pregnancy increase risks of attempted and completed suicide
within a year? A population‐based nested case
control study. BJOG 2018; 125(8): 983–90.
Shaohua L, Shorey S. Psychosocial interventions on
psychological outcomes of parents with perinatal loss:
A systematic review and meta-analysis. International
Journal of Nursing Studies 2021; 117: 103871.
Dimitriadis E, Menkhorst E, Saito S, Kutteh WH, Brosens JJ.
Recurrent pregnancy loss. Nat Rev Dis Primers 2020;
(1): 98.
Feodor Nilsson S, Andersen P, Strandberg‐Larsen K, Nybo
Andersen A. Risk factors for miscarriage from a
prevention perspective: a nationwide follow‐up study.
BJOG 2014; 121(11): 1375–85.
Zhang S, Yang Y, Xie X, Li H, Han R, Hou J, Sun J, Qian Z
(Min), Wu S, Huang C, Howard SW, Tian F, Deng W,
Lin H. The effect of temperature on cause-specific
mental disorders in three subtropical cities: A case
crossover study in China. Environment International
; 143: 105938.
Yu X, Miao H, Zeng Q, Wu H, Chen Y, Guo P, Zhu Y.
Associations between ambient heat exposure early in
pregnancy and risk of congenital heart defects: a large
population-based study. Environ Sci Pollut Res 2022;
(5): 7627–38.
Zhou W, Ming X, Chen Q, Liu X, Yin P. The acute effect
and lag effect analysis between exposures to ambient
air pollutants and spontaneous abortion: a case
crossover study in China, 2017–2019. Environ Sci
Pollut Res 2022; 29(44): 67380–9.
Yang D, Chen L, Yang Y, Shi J, Xu J, Li C, Wu Y, Ji X.
Influence of ambient temperature and diurnal
temperature variation on the premature rupture of
membranes in East China: A distributed lag nonlinear
time series analysis. Environmental Research 2021;
: 111145.
Nyadanu SD, Tessema GA, Mullins B, Pereira G. Prenatal
acute thermophysiological stress and spontaneous
preterm birth in Western Australia, 2000–2015: A
space-time-stratified
case-crossover
analysis.
International Journal of Hygiene and Environmental
Health 2022; 245: 114029.
Asamoah B, Kjellstrom T, Östergren P-O. Is ambient heat
exposure levels associated with miscarriage or
stillbirths in hot regions? A cross-sectional study
using survey data from the Ghana Maternal Health
Survey 2007. Int J Biometeorol 2018; 62(3): 319–30.
Sun X, Luo X, Cao G, Zhao C, Xiao J, Liu X, Dong M, Wang
J, Zeng W, Guo L, Wan D, Ma W, Liu T. Associations
of ambient temperature exposure during pregnancy
with the risk of miscarriage and the modification
effects of greenness in Guangdong, China. Science of
The Total Environment 2020; 702: 134988.
Liberati A. The PRISMA statement for reporting systematic
reviews and meta-analyses of studies that evaluate
healthcare interventions: explanation and elaboration.
BMJ 2009; 339(jul21 1): 2700-2700,.
Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page
MJ, Welch VA (editors). Cochrane Handbook for
Systematic Reviews of Interventions. Chichester
(UK): John Wiley & Sons; 2019.
Joanna Briggs Institute. Critical appraisal tools. http://
joannabriggs.org/research/critical-appraisal
tools.html. Accessed 26 April 2024. 2016; .
Wang KN, Bell JS, Chen EYH, Gilmartin-Thomas JFM,
Ilomäki J. Medications and Prescribing Patterns as
Factors Associated with Hospitalizations from Long
Term Care Facilities: A Systematic Review. Drugs
Aging 2018; 35(5): 423–57.
Chersich MF, Pham MD, Areal A, Haghighi MM, Manyuchi
A, Swift CP, Wernecke B, Robinson M, Hetem R,
Boeckmann M, Hajat S. Associations between high
temperatures in pregnancy and risk of preterm birth,
low birth weight, and stillbirths: systematic review
and meta-analysis. BMJ 2020; : m3811.
Davenport F, Dorélien A, Grace K. Investigating the
linkages between pregnancy outcomes and climate in
sub-Saharan Africa. Popul Environ 2020; 41(4): 397
Hajdu T, Hajdu G. Post-conception heat exposure increases
clinically unobserved pregnancy losses. Sci Rep 2021;
(1): 1987.
Hajdu T, Hajdu G. Climate change and the mortality of the
unborn. Journal of Environmental Economics and
Management 2023; 118: 102771.
Qu Y, Zhang W, Ryan I, Deng X, Dong G, Liu X, Lin S.
Ambient extreme heat exposure in summer and
transitional months and emergency department visits
and hospital admissions due to pregnancy
complications. Science of The Total Environment
; 777: 146134.
Wesselink AK, Wise LA, Hatch EE, Mikkelsen EM, Savitz
DA, Kirwa K, Rothman KJ. A Prospective Cohort
Study of Seasonal Variation in Spontaneous Abortion.
Epidemiology 2022; 33(3): 441–8.
Gericke GS, Hofmeyr GJ, Laburn H, Isaacs H. Does heat
damage fetuses? Med Hypotheses 1989; 29(4): 275–8.
Banks S, King SA, Irvine DS, Saunders PTK. Impact of a
mild scrotal heat stress on DNA integrity in murine
spermatozoa. Reproduction 2005; 129(4): 505–14.
Eisenberg ML, Sapra KJ, Kim SD, Chen Z, Buck Louis GM.
Semen quality and pregnancy loss in a contemporary
cohort of couples recruited before conception: data
from the Longitudinal Investigation of Fertility and
the Environment (LIFE) Study. Fertil Steril 2017;
(4): 613–9.
Robinson L, Id G, Sj C, M R, D M, S L, J K-B, A C. The
effect of sperm DNA Amadi JA, Odwe G, Obare F,
Sambai B and Kangwana B. Interventions addressing
the impacts of climate change on sexual and
reproductive health and rights in sub-Saharan Africa:
A scoping review. Plos one, 2025.
fragmentation on miscarriage rates: a systematic review and
meta-analysis.
Human reproduction (Oxford,
England) 2012; 27(10).
Sakkas D, Alvarez JG. Sperm DNA fragmentation:
mechanisms of origin, impact on reproductive
outcome, and analysis. Fertil Steril 2010; 93(4):
–36.
Stan CM, Boulvain M, Pfister R, Hirsbrunner-Almagbaly P.
Hydration for treatment of preterm labour. Cochrane
Database Syst Rev 2013; (11): CD003096.
Li D-K, Janevic T, Odouli R, Liu L. Hot tub use during
pregnancy and the risk of miscarriage. Am J Epidemiol
; 158(10): 931–7.
Schifano P, Lallo A, Asta F, De Sario M, Davoli M,
Michelozzi P. Effect of ambient temperature and air
pollutants on the risk of preterm birth, Rome 2001
Environ Int 2013; 61: 77–87.
Du S, Bai S, Zhao X, Lin S, Zhai Y, Wang Z, Wang Z. The
effect and its critical window for ambient temperature
and humidity in pregnancy on term low birth weight.
Environ Sci Pollut Res 2022; 29(36): 54531–42.
Wang H, Li J, Liu H, Guo F, Xue T, Guan T, Li J.
Association of maternal exposure to ambient
particulate pollution with incident spontaneous
pregnancy loss. Ecotoxicology and Environmental
Safety 2021; 224: 112653.
Wang F, Shi C, Dong J, Nie H. Association between ambient
temperature and atopic dermatitis in Lanzhou, China:
a time series analysis. Environ Sci Pollut Res 2021;
(47): 67487–95.
Basagaña X, Michael Y, Lensky IM, Rubin L, Grotto I,
Vadislavsky E, Levi Y, Amitai E, Agay-Shay K. Low
and High Ambient Temperatures during Pregnancy
and Birth Weight among 624,940 Singleton Term
Births in Israel (2010–2014): An Investigation of
Potential Windows of Susceptibility. Environ Health
Perspect 2021; 129(10): 107001.
Spolter F, Kloog I, Dorman M, Novack L, Erez O, Raz R.
Prenatal exposure to ambient air temperature and risk
of early delivery. Environment International 2020;
: 105824.
Bogan M, Al B, Kul S, Zengin S, Oktay M, Sabak M,
Gümüşboğa H, Bayram H. The effects of desert dust
storms, air pollution, and temperature on morbidity
due to spontaneous abortions and toxemia of
pregnancy: 5-year analysis. Int J Biometeorol 2021;
(10): 1733–9.
Strand LB, Barnett AG, Tong S. Maternal exposure to
ambient temperature and the risks of preterm birth and
stillbirth in Brisbane, Australia. Am J Epidemiol 2012;
(2): 99–107.
Gilbert-Barness E. Teratogenic causes of malformations.
Ann Clin Lab Sci 2010; 40(2): 99–114.
Nunes B, Paixão E, Dias CM, Nogueira P, Marinho Falcão
J. Air conditioning and intrahospital mortality during
the 2003 heatwave in Portugal: evidence of a
protective effect. Occup Environ Med 2011; 68(3):
–23.
Rogot E, Sorlie PD, Backlund E. Air-conditioning and
mortality in hot weather. Am J Epidemiol 1992;
(1): 106–16.
Article Metrics
Abstract View
: 437 times
Download : 166 times
Refbacks
- There are currently no refbacks.
