Alpha-Tocopherol Levels in Milk of Exclusively Breast-Feeding Mothers in Benin City, Nigeria
Abstract
The influence of prolonged breastfeeding on breast-milk alpha tocopherol was assessed in 112 lactating mothers practicing exclusive breast-feeding on term infants. The cross sectional study was carried out between May 1st and 30th, 2005 at the University of Benin/University of Benin Teaching Hospital, Benin City among lactating mothers. Employing the Quaife’s method, mean alpha-tocopherol values were determined in spot samples of breast milk. Though not significant mean Breast-milk (BM) alphatocopherol tended to decline with maternal age (p > 0.05) parity (p > 0.05) and duration of breastfeeding. Similarly, family socio-economic status did not significantly influence mean BM alphatocopherol levels. Exclusive and or prolonged breast feeding do not predispose the infant to low vitamin E supplies through the breast milk. Further studies are advocated to evaluate the effects of other biosocial variables on the levels of BM anti-oxidant vitamins including alpha-tocopherol (Afr J Reprod Health 2009; 13[2]:55-60).
RĖSUMĖ
Niveaux de tocophérol-alpha dans le lait des mères qui nourrissent leurs bébés exclusivement au sein à Benin City. Nous avons évalué l’influence de l’allaitement prolongé sur le tocophérol-alpha du lait maternel chez 112 mères allaitant qui pratiquent l’allaitement exclusive de leurs enfants nés à terme. L’étude transversale a été effectuée entre le 1e et le 30 mai 2005 à l’University of Benin Teaching Hospital auprès des mères allaitant. A l’aide de la méthode Quaife, les valeurs moyennes du tocophérolalpha ont été déterminés à travers des échantillons de taches du lait maternel. Quoique peu significatif, le lait maternel moyen (mm) du tocophérol-alpha avait la tendance à baisser avec l’âge maternel (p<0,05), la parité (0,05) et la durée de l’allaitement. De la même façon, la situation socio-économique familiale n’a pas influencé de manière significative les niveaux du tocophérol-alpha BM moyen. L’allaitement exclusif ou prolongé ne prédispose pas l’enfant à une provision baissée de la vitamine E à travers le lait maternel. Nous préconisons davantage d’études pour évaluer les effets d’autres variables biosociaux sur les niveaux des vitamines anti-oxidantes BM y compris le tocophérol-alpha (Afr J Reprod Health 2009; 13[2]:55-60).
KEYWORDS: Alpha tocopherol , Breast milk, Lactating mothers, Benin City
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Seven A, Sivelek S, Inci E, Inci F, Korkut N, Bureak G. Biochemical evaluation of oxidative stress in patients with laryngeal carcinoma. Turkish Arch Otolaryngol 1997; 35: 88 – 92.
Lackie JM, More AR, Connor JM. Cells and tissues in health and disease. In: Macsween
R N M and Whaley K (eds), Muir’s Textbook of Pathology, Kent, Edward
Arnold (Publishers) 1992: 23 – 5.
Stockman JA. Physiologic Anaemia. In: Behrman RE, Kliegman R M, Nelson WE, Vangham VC (eds) Nelson Textbook of Pediatrics, 14th edn, Philadelphia, W.B. Saunders Co (Publishers) 1992. p.1235.
Lachance AP. Future vitamins and antioxidants, RDAs for health promotion. Prev. Med 1996, 25: 46 –7.
Krebs NF, Hambridge KM. Normal
Childhood Nutrition and its Disorders. In:
Hay W W Jr, Hayward A R, Levin M J,
Sondheimer J M (eds), Current Paediatric Diagnosis and Treatment, 15th edn, New York, McGraw Hill Companies (Publishers) 1999: 249 – 61.
Friel JK, Sean MM, Matthew L, Gene RH, Garry RB. Milk from mothers of both premature and full-term infants provides better antioxidant protection than do infant formula. Paediatr Res 2002; 51: 612 – 8.
Neuhouser ML, Rock CL, Eldridge AL, Kristal AR, Patterson RE, Cooper DA et al. Serum concentration of retinal, alpha– tocopherol and the carotenoids are influenced by diet, race and obesity in a sample of healthy adolescents. J Nutr 2001; 131: 2184 –91.
African Journal of Reproductive Health Vol 13 No 2 June 2009
Lachili B, Faure H, Smail A, Zama N, Benlatreche C, Favier A, et al. Plasma vitamin A, E and beta-carotene levels in adult post-partum Algerian women. Int Vitam Nutr Res 1999; 69: 239 –42.
Buescher ES, Mcllhirhan SM. Antioxidant properties of human colostrum. Paediatr. Res. 1998; 24: 14 –9.
Omoigberale AI, Ibadin MO. The pattern of weight gain in exclusively breastfed infants, during the first six months of life in Benin City, Nigeria. Sahel Med J 1999; 2: 45 – 8.
Federal Ministry of Health Publications: Breast feeding; Nature’s way; Baby friendly Hospital Initiative, 1997.
Olusanya O, Okpere E, Ezimokhai M. The importance of social class in voluntary fertility control in a developing country. West Afr Med J 1985; 4: 205-11.
Quaife ML, Scriimshaw NS, Lowry OH.
Micro-method for assay of total tocopherol in blood serum. J Biol Chem 1949; 180: 1220 – 35.
Losonczy KG, Harris TB, Havlik RJ. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: The established populations for epidemiologic studies of the elderly. Am J Clin Nutr 1996; 64 : 190 – 6.
Yeum K, Ferland G, Patry J, Russell RM. Relationship between plasma carotenoids, retinal and tocopherol in mothers and newborn infants. J Am Coll Nutr 1998; 17: 442 –7.
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