The Effect of Endometrial Thickness on In vitro Fertilization (IVF)-Embryo Transfer/Intracytoplasmic Sperm Injection (ICSI) Outcome
), Onuh S.O(2), Ebeigbe P(3), Shaibu I(4), Wada I(5), Ikimalo J.I(6), Okpere E.E(7),
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Corresponding Author
Abstract
The value of measuring the endometrial thickness and studying the endometrial receptivity in the context of assisted conception remains a contentious issue. A prospective analysis was carried out to determine the effect of endometrial thickness on IVF - embryo transfer / ICSI outcome in dedicated Assisted Reproductive Technology (ART) units in Abuja and Rivers State, Nigeria. Two hundred and fifty one patients who met the inclusion criteria were analysed. They were grouped on the basis of endometrial thickness into 3 groups; <7 mm, 7 – 14 mm and >14 mm. The main outcome measure was clinical pregnancy. There were significantly more pregnancies in the 7 – 14 mm endometrial thickness group compared to the <7 mm and >14mm groups, p=0.004 and p<0.0001 respectively. The findings suggest that following IVF/ICSI, significantly more pregnancies occurred when the endometrial thickness was between 7 and 14 mm (Afr J Reprod Health 2009; 13[1]:113-121).
RĖSUMĖ
L’effet de l’épaisseur endomètre sur la fécondation in vitro (FIV) le transfert de l’embryon/le résultat de l’injection intracytoplasmique du sperme. La valeur obtenue quand on mesure l’épaisseur d’endomètre et quand on étudie la réceptivité d’endomètre dans le contexte d’une conception assistée reste un problème controversé. Une analyse prospective a été menée pour déterminer l’effet de l’épaisseur d’endomètre sur la FIV-le transfert de l’embryon/IIS dans les centres de la Technologie de la Reproduction Assistée à Abuja et dans l’état de Rivers, au Nigéria. Deux cent cinquante patientes qui ont satisfait les critères d’inclusion ont été analysées. Elles ont été regroupées selon l’épaisseur d’endomètre en trois groupes : < 7mm, 7-14mm et > 14mm. Le résultat de la mesure le plus important était la grossesses parmi le groupe de < 7mm et > 14mm, p=0,004 et p<0,0001 respectivement. Les résultats indiquent qu’à travers la FIV/IIS, ils se produisaient de manière significative, plus de grossesses quand l’épaisseur d’endomètre était entre 7 et 14mm (Afr J Reprod Health 2009; 13[1]: 113121).
KEYWORDS: Endometrial thickness, IVF/ICSI, Pregnancy
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