This study aimed to explore some correlates and potential reproductive consequences of consanguinity. We analysed data for 8515 ever-married women aged 15-49 derived from a household survey conducted in 2017 in six governorates. The prevalence of consanguineous marriage was 35.9%. The odds (OR (95%CI)) of consanguinity were higher in rural southern governorates (3.68 (3.03-4.46)), with less than secondary education (1.55 (1.42-1.7)), with unemployment (1.74(1.48-2.04)) and in the lowest wealth quintile (3.09 (2.66-3.6)). After adjusting for residence, education, wealth, age at marriage and the number of children; the OR (95%CI) for spontaneous abortion and still births with consanguinity were 1.31 (1.09-1.59) and 1.63 (1.18-2.25) respectively. Consanguinity remains highly prevalent in Egypt especially in rural southern governorates. Women empowerment in terms of attaining higher education and employment may reduce the problem. Consanguinity appears to be associated with adverse reproductive outcomes including spontaneous abortion and still birth. (Afr J Reprod Health 2022; 26[12s]: 48-56).

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consanguineous communities: lessons from a

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doi:10.1136/bmj.331.7530.1475

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Jordan. Saudi medical journal. 2007/07//undefined

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contemporary world. Human heredity. 2014

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Yunis K, Mumtaz G, Bitar F, Chamseddine F, Kassar M,

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Rashkidi J, Makhoul G and Tamim H.

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Consanguineous marriage and congenital heart

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defects: a case-control study in the neonatal period.

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American journal of medical genetics Part A.

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doi:10.1002/ajmg.a.31309

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Al-Gazali L and Ali BR. Mutations of a country: a mutation

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review of single gene disorders in the United Arab

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Emirates (UAE). Human mutation.

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/05//undefined 2010;31(5):505-520.

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doi:10.1002/humu.21232

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Corry PC. Consanguinity and prevalence patterns of

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inherited disease in the UK Pakistani community.

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Human heredity. 2014 2014;77(1-4):207-216.

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doi:10.1159/000362598

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Sheridan E, Wright J, Small N, Corry PC, Oddie S, Whibley

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C, Petherick ES, Malik T, Pawson N, McKinney PA

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and Parslow RC. Risk factors for congenital anomaly

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in a multiethnic birth cohort: an analysis of the Born

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in Bradford study. Lancet (London, England).

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/10/19/ 2013;382(9901):1350-1359.

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doi:10.1016/S0140-6736(13)61132-0

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Anwar WA, Khyatti M and Hemminki K. Consanguinity

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and genetic diseases in North Africa and immigrants

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to Europe. European journal of public health.

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/08//undefined 2014;24 Suppl 1:57-63.

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doi:10.1093/eurpub/cku104

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Oniya O, Neves K, Ahmed B and Konje JC. A review of the

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reproductive consequences of consanguinity.

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European journal of obstetrics, gynecology, and

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reproductive biology. 2019/01//undefined

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;232:87-96. doi:10.1016/j.ejogrb.2018.10.042

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Chaman R, Gholami Taramsari M, Khosravi A, Amiri M,

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Holakouie Naieni K and Yunesian M. Consanguinity and neonatal death: a nested case-control study.

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Journal of family & reproductive health. 2014/12//

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;8(4):189-193.

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Kerkeni E, Monastiri K, Saket B, Guediche MN and Ben

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Cheikh H. Interplay of socio-economic factors,

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consanguinity, fertility, and offspring mortality in

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Monastir, Tunisia. Croatian medical journal.

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/10//undefined 2007;48(5):701-707.

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Khayat RG and Saxena PC. Consanguinity and its effect on

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fertility and infant and child mortality in Egypt. 2004:

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Maghsoudlou S, Cnattingius S, Aarabi M, Montgomery

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SM, Semnani S, Stephansson O, Wikström AK and

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Bahmanyar S.. Consanguineous marriage,

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prepregnancy maternal characteristics and stillbirth

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risk: a population-based case–control study. Acta

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Obstetricia et Gynecologica Scandinavica.

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/10/01/ 2015;94(10):1095-1101.

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doi:10.1111/aogs.12699

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Assaf S, Khawaja M, DeJong J, Mahfoud Z and Yunis K.

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Consanguinity and reproductive wastage in the

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Palestinian Territories. Paediatric and perinatal

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epidemiology. 2009/03//undefined 2009;23(2):107-

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doi:10.1111/j.1365-3016.2008.00988.x

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Islam MM. Effects of consanguineous marriage on

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reproductive behaviour, adverse pregnancy outcomes

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and offspring mortality in Oman. Annals of human

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biology. 2013/05//undefined 2013;40(3):243-255.

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doi:10.3109/03014460.2012.760649

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Mokhtar MM and Abdel-Fattah MM. Consanguinity and

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advanced maternal age as risk factors for

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reproductive losses in Alexandria, Egypt. European

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journal of epidemiology. 2001 2001;17(6):559-565.

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