Genital Infections Among Antenatal Care Attendees in Cape Verde

Hans F. Wessel, Bijörn Herrmann, Alice Dupret, Filomena Moniz, Carlos Brito, Staffan Bergstrom

Abstract

In a cross-sectional study, 350 pregnant Capeverdian women were examined to assess the prevalence of Chlamydia trachomatis infection (CT), Neisseria gonorrhoeae infection (NG) and Bacterial vaginosis (By). Among various analytic methods used, the polymerase chain reaction PCR (for NG, CT) yielded a higher detection rate than did direct microscopy or culture (NG), or direct immuno-fluorescence (CT). Since the PCR analytic of air-dried specimens is not hampered by harsh storage and transport conditions, it could serve to validate other detection methods where laboratory facilities are suboptimal. Among socio-demographic risk factors young age, and currently living alone, were significantly associated with infection. (Afr I Reprod Health 1998;(2) 1:32—40)

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References

Hook III EW, Handsfield HH. Gonococcal infections in the adult. In: Holmes KK, Mârdh PA, Sparling PF, Wiesner PJ, eds. Sexually Transmitted Diseases, 2nd ed. New York: McGraw-Hill, 1990: 149—60.

Stamm WE, Holmes KK. Chiamydia trachomatis infections of the adult. In: Holmes KK, Mrdh PA, Sparling PF, Wiesner PJ, eds. Sexually Transmitted Diseases, 2nd ed. New York: McGraw- Hill, 1990:181—93.

Jamison DT, Mosley, WH. Disease control priorities in developing countries: health policy responses to epidemiological change. Am J Public Health 1991;81:15—22.

Brunham RC, Embree JE. Sexually transmitted diseases: current and future dimensions of the problem in the third world. In: Germaine A, Holmes KK, Piot P, Wasserheit J, eds. Reproductive Tract Infection: Global impact and priorities for women’s reproductive health. New York: Plenum,1992:35—58.

Holmes KK. Human ecology and behaviour and sexually transmitted bacterial infections. Proc NatlAcad Sci 1994;91:2448—55.

Laga M, Nzila N, Goeman J. The interrelationship of sexually transmitted diseases and HIV infection: implications for the control of both epidemics in Africa. AIDS 1991;5(suppl 1): 55-63.

Sobel JD. Vaginitis and vaginal flora: controversies abound. Current Opinion in Infectious Diseases 1996;9:42—7.

Berger BJ, Kolton S, Zenilman JM, Cummings MC, Feldman I, McCormack WM. Bacterial vaginosis in lesbians: a sexually transmitted disease. Clin InfDis 1995;21:1402—5.

McCoy MC, Katz VL, Kuller JA, Killam AP, Livengood III CH. Bacterial vaginosis in pregnancy: an approach for the 1990s. ObstetGynecol Survey 1995;50:482—8.

Larsson PG, Platz-Christensen II, Thejls H, Forsum U, Phhlson C. Incidence of pelvic inflammatory disease following first trimester legal abortion in women with bacterial vaginosis after treatment with metronidazole: a double-blind randomized study. Am I Obstet Gynecol 1992;166:100-3.

Wessel H, Cnattingius S, Bergstrom S, DupretA, Reitmaier P. Maternal risk factors for preterm birth and low birthweight in Cape Verde. Acta Obstet Gynecol Scand 1 996;75:360—6.

Herrmann B, Nystrom T, Wessel H. Detection of Neisseria gonorrhoeae from air-dried genital samples by single-tube nested PCR. I Clin Microbiol 1996;34:2548—5 1.

Gilroy CB, Thomas BJ, Taylor-Robinson D. Small numbers of Chlamydia trachomatis elementary bodies on slides detected by the polymerase chain reaction. I Gun Pathol 1992;45:531—2.

Larsson PG, Platz-Christensen JJ. Enumeration of clue cells in rehydrated air-dried vaginal smears for the diagnosis of bacterial vaginosis. Obstet Gynecol 1990;76:727—30.

Dean AD, Dean JA, Burton AH, Dicker RC. Epi Info: a word, database, and statistical system for epidemiology on micro-computers. USD, Incorporated, Stone Montain, Georgia, USA, 1 990;74-6,133—7,355—60.

de Brito CPF. Boletim Epidemiologico HIV 1994. PNLS Maio 1995:3—9 (in Portuguese).

Alary M, Joly JR, Moutquin JM, Labrecque M. Strategy for screening pregnant women for chlamydial infection in a low-prevalence area. Obstet Gynecol 1993;82:399—404.

Shaw E, Roberts D, Conner PD. Prevalence of and risk factors for Chlarnydia in a rural pregnant population. Journal of Family Practice 1995;4l (3):257-60.

Herrmann B, Egger M. Genital Chlamydia trachomatis infections in Uppsala county, Sweden 1985-1993: declining rates for how much longer? Sexually Transmitted Diseases 1995;22:253-60.

Adler MW. Sexually transmitted diseases control in developing countries. Genitourin Med I 996;72:83—8.

Mason PR, Katzenstein DA, Chimbira THK, Mtimavalye L, and the puerperal sepsis study group. Vaginal flora of women admitted to hospital with signs of sepsis following normal delivery, caesarian section or abortion. CentralAfrican Journal of Medicine 1989;35:344—51.

Beaujean G, Willems, I. Prevalence of Chlamydia trachomatis infection in pregnant women in Zaire. Genitourin Med I 990;66: 124—5.

Tswana SA, Nystrom L, Moyo SR, et al. Hospital-based study of sexually transmitted diseases at Murewa rural district hospital, Zimbabwe 1991—1992. Sexually Transmitted Diseases, 1995;Jan—Feb: 1—6.

Moses 5, Manji F, Bradley JE, et al. Impact of user fees on attendance at a referral centre for sexually transmitted diseases in Kenya. Lancet 1992;340:463-6.

Mhalu F, Balampama P, Makwaya C, et al. Integration of Sexually Transmitted Diseases in Reproductive Health Services for Women. Proceedings of the 6th SAREC Regional Reproductive Health Workshop; March 18—22,1996:6—7.

Thomason JL, Gelbart SM, Sobieski VT, Anderson RJ, Schulen MB, Hamilton PR. Effectiveness of Gonozyme for Detection of gonorrhea in low- risk pregnant and gynecologic populations. Sexually Transmitted Diseasesl989;16:28—31.

Vuylsteke B, Bastos R,Barreto J, Crucitti T, Folgosa E, Mondlane J, Dusauchoit T, Piot P, Laga M. High prevalence of sexually transmitted diseases in a rural area in Mozambique. Genitourin Med 1993;69:427—430.

Riduan JM, Hillier SL, Utomo B, Wijknjosastro G, Linnan M, Kandun N. Bacterial vaginosis and prematurity in Indonesia: Association in early and late pregnancy. Am I Obstet Gynecol 1993;169:175-8.

Josoef MR, Hillier SL, Wiknjosastro G, et al. Intravaginal clindamycin treatment for bacterial vaginosis: Effects on preterm delivery and low birth weight. Am I Obstet Gynecol 1995;173: 1527-31.

Hay PE, Morgan DJ, Ison CA, et al. A longitudinal study of bacterial vaginosis during pregnancy. Bri Obstet Gynaecol 1994;l01:1048—53.

Hay PE, Thomas BJ, Homer PJ, MacLeod E, Renton AM, Taylor-Robinson D. Chiamydia trachomatis in women: the more you look, the more you find. Genitourin Med 1994;70:97—1 00.

Claas HCJ, Wagenvoort JHT, Niesters HGM, Tio TT, van Rijsoort JH, Quint WGV. Diagnostic value of the polymerase chain reaction for Chlamydia detection as determined in a followup study. J Clin Microbiol 199 1;29:42—5.

Vogels WHM, van Voorst Vader PC, Schroder FP. Chiamydia trachomatis in a high-risk population: comparison of polymerase chain reaction and cell culture for diagnosis and follow-up. I Clin Microbiol 1993;31:1103—7.

McCormack WM, Alpert S, McComb DE, Nichols RL, Semine DZ, Zinner SH. Fifteen- month follow-up study of women infected with Chlamydia trachomatis. N Eng J Med 1979;300:123—5.

BeattyWL, Byrne GI, Morrison RP. Repeated and persistent infection with Chlamydia and the development of chronic inflammation and disease. Trends in Microbiology 1994;2:94—8.

Grosskurth H, Mosha F, Todd J, et al. Impact of improved treatment of sexually transmitted diseases on HIV infection in rural Tanzania: randomised controlled trial. Lancet 1995;346:530-6.

La Ruche G, Lourgnon F, Digbeu N. Therapeutic algortihms for the management of sexually transmitted diseases at the peripheral level in Côte d’Ivoire: assessment of efficacy and cost. Bull WHO 1995;73:305—13.

Mârdh PA, Danielsson D. Neisseria gonorhhoeae. In: Homes KK, Märdh PA, Sparling PF, Wiesner PJ, eds. Sexually transmitted diseases. New York: McGraw-Hill, 1990:903—16.

Larsson PG, Platz-Christensen JJ. Enumeration of clue cells in Enumeration of clue cells in rehydrated air-dried vaginal wet smears for the diagnosis of bacterial vaginosis. Obstet Gynecol 1990;76:727—30.

Aladesanmi AFK, Muntaz G, Mabey DCW. Letter to the Editor: Prevalence of cervical chlamydial infection in antenatal clinic attenders in Lago, Nigeria. Genitourin Med 1989;65:130.

Mabey DCW, Whittle HC. Genital and neonatal chlamydial infections in a trachoma endemic area. Lancet 1982;ii:301—2.

Leclerc A, Frost E, Collet M, Goeman J, Bedjabaga L. Urogenital Chlamydia trachomatis in Gabon: an unrecognised epidemic. Genitourin Med 1988;64:308—1 1.

Nugent RP, Krohn MA, Hillier SL. The reliability of diagnosing bacterial vaginosis is improved by a standardized method of Gram stain interpretation. I Clin Micro biol 1991;29:297—301.

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